A compounded acne cream that combines three approaches in one — clindamycin 1%, spironolactone 5% and tretinoin 0.025% — prescribed online, reviewed by licensed providers, prepared by a U.S. 503A pharmacy and shipped discreetly to every state except Alabama, Arkansas, California, Florida, Kentucky and South Carolina.
$357 for 3 months
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Supply
One payment for a 3-month supply.
A few private questions, then a licensed provider reviews your answers.
The formula
A compounded prescription acne cream
Clarity is a compounded acne cream with three prescription actives, each aimed at a different cause of breakouts. Ours is compounded by a U.S. 503A pharmacy; compounded formulas are not themselves FDA-approved.
Clindamycin is a topical antibiotic that reduces acne bacteria and inflammation, spironolactone is an anti-androgen applied to the skin to target hormone-driven oil, and tretinoin keeps pores from clogging.
Through ForbiddenRx, a licensed provider reviews your skin and history and decides whether this cream, and how it is used, is right for you.
Acne forms when oil and dead skin clog pores, bacteria (C. acnes) multiply inside them, and the skin reacts with inflammation. Hormones (androgens) drive oil production, which is why acne often flares with hormonal changes. Treatments that act on more than one of these causes at once are a common prescription approach.
Dead cells and oil plug the pore. Tretinoin speeds turnover so pores stay clear.
Clindamycin targets bacteria and inflammation; spironolactone targets hormone-driven oil.
Over-the-counter acne products usually rely on one active, such as benzoyl peroxide or salicylic acid. Clarity combines three prescription actives, with a provider deciding whether it fits your skin.
| Benzoyl peroxide / salicylic (OTC) | Single prescription topical | Clarity Cream (Rx) | |
|---|---|---|---|
| Actives | One | One | Three: clindamycin, spironolactone, tretinoin |
| Targets | Bacteria or pores | One cause | Pores, bacteria, inflammation & oil |
| Provider involved | No | Yes | Yes — reviews your skin & history |
| Formula | One-size-fits-all | Fixed | Compounded per prescription |
Acne treatment is usually a routine rather than a quick fix. Your provider decides what fits your skin and may adjust your plan over time.
Three actives, three causes of breakouts.
Tretinoin 0.025% speeds cell turnover so dead cells and oil don't plug pores.
Clindamycin 1%, a topical antibiotic, reduces acne bacteria and inflammation.
Spironolactone 5% is an anti-androgen applied to the skin; it is studied less than the oral form.
It's for adults with acne. A provider confirms it's appropriate for your skin and history.
Acne that over-the-counter products haven't controlled.
Breakouts around the jaw and chin that flare with hormonal changes.
Red, tender breakouts as well as blackheads and congestion.
Skin that clogs easily and stays oily through the day.
Avoid it if you're pregnant, trying to conceive or breastfeeding, because it contains tretinoin and spironolactone. Tell your provider about broken or irritated skin, eczema, a history of colitis or bowel problems (clindamycin), or a past reaction to any of the three actives.
You complete a private online visit, a licensed provider reviews it, and — if appropriate — your prescription ships to your door. No insurance required, no in-person appointment, no waiting room.
A few private questions about your skin, goals, and history, on your own time.
A provider licensed in your state reviews your information and, if appropriate, writes your prescription.
Shipped from a U.S. pharmacy in plain, unmarked packaging to every state except Alabama, Arkansas, California, Florida, Kentucky and South Carolina. Reorder anytime from your dashboard, and our support team is an email or call away.
Your price is shown before you pay. No insurance needed.
This is a compounded topical. How much you use and how often are set by the provider who reviews your visit. We deliberately do not publish a regimen here, because that is a clinical decision about you, not a product specification.
It contains tretinoin and spironolactone. Do not use it if you are pregnant, planning to become pregnant, or breastfeeding. Tell your provider about pregnancy, all medications and any skin conditions before starting.
Possible side effects include:
Stop and contact your provider if you develop severe irritation, a rash, or severe or persistent diarrhea.
A side-by-side look at the prescription skin options available through ForbiddenRx. Your provider helps you choose what's right.
| Treatment | What it is | Best for | Form | For | Rx required |
|---|---|---|---|---|---|
| Tretinoin | A prescription retinoid (vitamin A) | Acne + anti-aging | Cream / gel | Adults | Yes |
| Melasma Cream | Tretinoin / hydrocortisone / hydroquinone 4% or 8% | Melasma & dark patches | Cream | Adults | Yes |
| Luminous Gel | Kojic / tranexamic acid / tretinoin | Melasma, hydroquinone-free | Gel | Adults | Yes |
| Clarity Cream This page | Clindamycin / spironolactone / tretinoin | Acne | Cream | Adults | Yes |
| Rosacea Cream | Azelaic acid / ivermectin / metronidazole | Rosacea | Cream | Adults | Yes |
| Anti-Aging Night Cream | Estriol / tretinoin / vitamin C | Fine lines & firmness | Night cream | Adults | Yes |
| Under-Eye Cream | Caffeine / tretinoin / glycolic acid | Dark circles & puffiness | Eye cream | Adults | Yes |
| Scar Gel | Silicone / betamethasone / lidocaine | Raised scars | Gel cream | Adults | Yes |
| GHK-Cu Cream | A copper-peptide repair cream | Firmness & recovery | Cream | Adults | Yes |
It combines tretinoin to keep pores clear, clindamycin to reduce acne bacteria and inflammation, and spironolactone, an anti-androgen applied to the skin, aimed at hormone-driven oil.
No. Here it is applied to the skin in a cream, not taken by mouth. Topical spironolactone is studied less than the oral form, and your provider decides whether it fits your skin.
Acne improves gradually. Many people notice changes over several weeks of consistent use, sometimes after an early flare. Results vary.
Yes. Tretinoin increases sun sensitivity, so use a broad-spectrum SPF every morning.
No. It contains tretinoin and spironolactone, which should be avoided during pregnancy, while trying to conceive, and while breastfeeding.
Physicians, NPs & PAs licensed in your state
U.S.-based compounding partners
We confirm your state during intake
Complete a private online visit and a licensed provider decides whether Clarity cream is right for you, and how to use it.
Written by ForbiddenRx and checked against FDA prescribing information and published sources · Updated October 2026. It is general information, not a review of your own health; your provider decides what is right for you. It is provided for general educational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Always talk with a licensed provider about your individual skin and health.
This page is educational and is not medical advice.